Limbaugh: Michael J. Fox Exploited Disease
WASHINGTON, Oct. 24, 2006 (CBS/AP) His body visibly wracked by tremors, actor Michael J. Fox appears in a political ad that was the subject of widespread discussion on Monday after conservative radio commentator Rush Limbaugh claimed Fox was "either off his medication or acting."
A victim of Parkinson's disease, Fox speaks out in the ad for Missouri Democratic Senate candidate Claire McCaskill, who supports embryonic stem cell research.
"I think this is exploitative in a way that's unbecoming of either Claire McCaskill or Michael J. Fox," Limbaugh said on his syndicated show.
On his Web site Tuesday, Limbaugh appeared to back away from his accusation.
"All I'm saying is I've never seen him the way he appears in this commercial for Claire McCaskill," says Limbaugh. "So I will bigly, hugely admit that I was wrong, and I will apologize to Michael J. Fox, if I am wrong in characterizing his behavior on this commercial as an act, especially since people are telling me they have seen him this way on other interviews and in other television appearances."
[img]http://wwwimage.cbsnews.com/common/images/bug_video.gif[/img] Watch Claire McCaskill's ad featuring Michael J. Fox here.
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"As you might know I care deeply about stem cell research," says Fox, who has struggled with Parkinson's disease for more than a decade. "In Missouri you can elect Claire McCaskill, who shares my hope for cures."
McCaskill has made support for the research a key part of her campaign to unseat Sen. Jim Talent. The Republican incumbent opposes the research as unethical, saying it destroys human embryos.
The new ad debuted prominently Saturday night during Game 1 of the World Series between the St. Louis Cardinals and the Detroit Tigers and will continue airing statewide this week, a campaign spokeswoman said.
Debate over stem cell research looms large in Missouri, where voters are considering a ballot measure that would amend the state constitution to protect all federally allowed forms of the research, including embryonic stem cell research. The scientific study holds promise in the search to cure diseases like Parkinson's and Alzheimer's.
"Unfortunately, Senator Jim Talent opposes expanding stem cell research," Fox says in the 30-second spot. "Senator Talent even wanted to criminalize the science that gives us a chance for hope."
Talent's campaign called the ad a false attack.
"Senator Talent supports medical research including stem cell research that doesn't involve cloning or destroying a human embryo," said Talent spokesman Rich Chrismer.
Earlier this year, Talent withdrew his support for a Senate bill that would ban all embryonic stem cell research and impose a million-dollar fine and jail sentence on violators. But he opposes the Missouri ballot initiative, claiming it would "make cloning human life at the earliest stage a constitutional right."
Supporters of the state referendum deny that assertion, noting the language of the proposed constitutional amendment explicitly bans human cloning.
McCaskill, running even with Talent in the latest polls, hopes to get a boost from aligning herself with support for the ballot measure, which recent polls show has the support of 58 percent of likely voters. Backers of the measure have raised nearly $29 million toward its passage, the costliest political campaign in Missouri history.
Fox's ad urges voters that "what you do in Missouri matters to millions of Americans. Americans like me." The ad ends with a picture of McCaskill and her voice approving the message.
A native of Canada, Fox became an American citizen in 2000 and has been politically active for Democratic causes. He campaigned for John Kerry in the 2004 presidential race and lobbied Congress to lift President Bush's restrictions on funding for stem cell research.
http://www.cbsnews.com/stories/2006/10/24/...in2121910.shtmlBased upon this information and past interviews I've seen with Fox where he did the rocking back and forth bit, I personally don't think he faked it or went off his drugs.
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Is there any treatment? At present, there is no cure for PD, but a variety of medications provide dramatic relief from the symptoms. Usually, patients are given levodopa combined with carbidopa. Carbidopa delays the conversion of levodopa into dopamine until it reaches the brain. Nerve cells can use levodopa to make dopamine and replenish the brain's dwindling supply. Although levodopa helps at least three-quarters of parkinsonian cases, not all symptoms respond equally to the drug. Bradykinesia and rigidity respond best, while tremor may be only marginally reduced. Problems with balance and other symptoms may not be alleviated at all. Anticholinergics may help control tremor and rigidity. Other drugs, such as bromocriptine, pergolide, pramipexole, and ropinirole, mimic the role of dopamine in the brain, causing the neurons to react as they would to dopamine. An antiviral drug, amantadine, also appears to reduce symptoms. In May 2006, the FDA approved rasagiline to be used along with levodopa for patients with advanced PD or as a single-drug treatment for early PD.
In some cases, surgery may be appropriate if the disease doesn't respond to drugs. A therapy called deep brain stimulation (DBS) has now been approved by the U.S. Food and Drug Administration. In DBS, electrodes are implanted into the brain and connected to a small electrical device called a pulse generator that can be externally programmed. DBS can reduce the need for levodopa and related drugs, which in turn decreases the involuntary movements called dyskinesias that are a common side effect of levodopa. It also helps to alleviate fluctuations of symptoms and to reduce tremors, slowness of movements, and gait problems. DBS requires careful programming of the stimulator device in order to work correctly.What is the prognosis?PD is both chronic, meaning it persists over a long period of time, and progressive, meaning its symptoms grow worse over time. Although some people become severely disabled, others experience only minor motor disruptions. Tremor is the major symptom for some patients, while for others tremor is only a minor complaint and other symptoms are more troublesome. No one can predict which symptoms will affect an individual patient, and the intensity of the symptoms also varies from person to person.
http://www.ninds.nih.gov/disorders/parkins...e_any_treatment